Publications

Referred Journal Articles

  1. Pol, M.; Gao, H.; Fox, J. M.; Jia, X.* "Integrin–Binding Peptide Cooperates with Soluble TGF–β1 to Promote Metastasis in an Engineered Model of Prostate Cancer" ACS Biomat. Sci. & Eng., minor revision, 2025, in press.
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  2. Metkari, A. S.; Witt, R. L.; Cognetti, D. M.; Dhong, C.; Jia, X.* "Promoting Polarization and Differentiation of Primary Human Salivary Gland Stem/Progenitor Cells in Protease–Degradable Hydrogels via ROCK Inhibition" ACS Appl. Mater. & Interfaces, 2025, 17, 18083–18095. Link
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  3. Ramaraj, P. K.; Pol, M.; Scinto, S. L.; Jia, X.*; Fox, J. M.* "Covalent Attachment of Functional Proteins to Microfiber Surfaces via a General Strategy for Site–Selective Tetrazine Ligation" ACS Appl. Mater. & Interfaces, 2024, 16, 63195–63206. Link
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  4. Gao, H.; Pol, M.; Makara, C. A.; Song, J.; Zhang, H.; Zou, X.; Benson, J. M.; Burris, D. J.; Fox, J. M ; Jia, X.* "Bioorthogonal Tuning of Matrix Properties during 3D Cell Culture to Induce Morphological and Phenotypic Changes" Nat Protoc, 2024, in press, DOI : 10.1038/s41596-024-01066-z. Link
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  5. Gao, H.; Zhang, T.; Langenstein, M. G.; Xie, W.; Udan, S.; Zhang, Z.; Saven, J. G.; Bai, S.; Pochan, D. J.; Fox, J. M.;Jia, X.* "High Molecular Weight Protein–Like Semiflexible Chains via Bioorthogonal Polymerization of Coiled–Coil Peptides" Macromolecules, 2024, 57, 9585–9594. Link
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  6. Fowler, E. W.; Witt, R. L.; Jia, X.* "Basement Membrane Mimetic Hydrogel Cooperates with ROCK Inhibitor to Promote the Development of Acini–Like Salivary Gland Spheroids" Advanced NanoBiomed Res, 2023, 3 , 2300088. Link
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  7. Guo, T.; Zou, X. ; Sundar, S.; Jia, X.; Dhong, C.* "In Situ Viscoelastic Properties of Cellular Monolayers via Graphene Strain Sensing of Elastohydrodynamic Phenomena" Lab Chip, 2023, 23, 4067–4087. Link
  8. Zou, X.; Zhang, H.; Benson, J. M.; Gao, H.; Burris, D. L.; Fox, J. M.; Jia, X.* "Modeling the Maturation of the Vocal Fold Lamina Propria Using a Bioorthogonally Tunable Hydrogel Platform" Adv. Healthcare Mater., 2023, 2301701. Link
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  9. Metkari, A. S.; Fowler E. W.; Witt, R. L.; Jia, X.* "Matrix Degradability Contributes to the Development of Salivary Gland Progenitor Cells with Secretory Functions" ACS Appl. Mater. Interfaces, 2023, 27, 32148–32161. Link.
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  10. Pol, M.; Gao, H.; Zhang, H.; George, O. J.; Fox, J. M.; Jia, X.* "Dynamic Modulation of Matrix Adhesiveness Induces Epithelial–to–Mesenchymal Transition in Prostate Cancer Cells in 3D" Biomaterials, 2023, 299, 122180. Link.
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  11. Song, J.; Gao, H; Zhang, H.; George, O. J.; Hillman, A. S.; Fox, J. M.; Jia, X.* "Matrix Adhesiveness Regulates Myofibroblast Differentiation from Vocal Fold Fibroblasts in a Bio–orthogonally Cross-linked Hydrogel" ACS Appl. Mater. Interfaces, 2022, 14, 51669–51682. Link.
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  12. Fowler, E. W.*; van Venrooy, E. J.; Witt, R. L.; Jia, X.* "A TGFβR inhibitor represses keratin–7 expression in 3D cultures of human salivary gland progenitor cells" Sci. Rep., 2022, 12, 15008. Link.
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  13. George, O. J; Song, J.; Benson, J. M.; Fang, Y.; Zhang, H.; Burris, D. L.; Fox, J. M.*; Jia, X.* "Tunable Synthesis of Hydrogel Microfibers via Interfacial Tetrazine Ligation" Biomacromolecules, 2022, 23, 3017 – 3030. Link.
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  14. Fowler, E. W.; Ravikrishnan, A.; Witt, R. L.; Pradhan-Bhatt, S.; Jia, X.* "RGDSP–Decorated Hyaluronate Hydrogels Facilitate Rapid 3D Expansion of Amylase–Expressing Salivary Gland Progenitor Cells" ACS Biomat. Sci. & Eng., 2021, 7, 5749 – 5761. Link.
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  15. Wang, S.; Liu, S.; Sulkanen, A.; Fox, J. M.; Jia, X.*; Liu, G.–Y.* "Controlled Molecular Assembly of Tetrazine Derivatives on Surfaces" CCS Chem., 2021, 3, 1789–1799. Link.
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  16. Wang, C.; Zhang, H.; Zhang, T.; Zou, X.; Wang, H.; Rosenberger, J.; Vannam, R.; Trout, W.; Grimm, J. B.; Lavis, L. D.; Thorpe, C.; Jia, X.*; Li, Z.*; Fox, J.M.* "Enabling in vivo Photocatalytic Activation of Rapid Bioorthogonal Chemistry by Repurposing Si–Rhodamine Fluorophores as Cytocompatible Far–Red Photocatalysts" J. Am. Chem. Soc., 2021, 143, 10793–10803. Link.
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  17. Ravikrishnan, A.; Fowler, E. W.; Stuffer, A. J.; Jia, X.* "Hydrogel–Supported, Engineered Model of Vocal Fold Epithelium" ACS Bmat. Sci. & Eng., 2021, 7, 4305 – 4317. Link.
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  18. Scott, R. A.; Fowler, E. W.; Jia, X.; Kiick, K. L.; Akins, R. E.* "Regulation of neovasculogenesis in co–cultures of aortic adventitial fibroblasts and microvascular endothelial cells by cell–cell interactions and TGF–β/ALK5 signaling" PLoS One, 2020, 15, e0244243. Link.
  19. Feng, H.; Zhang, H.; Wang, M.; Vannam, R.; Wang, H.; Yan, X.; Ouyang, W.; Jia, X.; Fox, J. M.*; Li, Z.* "Improving Tumor–to–Background Contrast Through Hydrophilic Tetrazines: The Construction of 18F Labeled PET Agents Targeting Non–Small Cell Lung Carcinoma" Chem. Eur. J., 2020, 26, 4690–4694. Link.
  20. Paik, B.; Calero-Rubiob, C.; Lee, J. Y.; Jia, X.; Kiick, K. L.*; Roberts, C. J.* "Characterizing aggregate growth and morphology of alanine–rich polypeptides as a function of sequence chemistry and solution temperature from scattering, spectroscopy, and microscopy" Biophy. Chem., 2020, 267, 106481. Link.
  21. Ravikrishnan, A.; Zhang, H.; Fox, J. M.*; Jia, X.* "Core–Shell Microfibers via Bioorthogonal Layer–by–Layer Assembly" ACS Macro Lett., 2020, 9, 1369–1375. Link.
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  22. Zerdoum, A. B.; Saberi, P.; Stuffer, A. J.; Kelly, D. J.; Duncan, R. L.; Mongeau, L.; Jia, X.* "Regulation of Stem Cell Function in an Engineered Vocal Fold–Mimetic Environment" Regen Eng Transl Med, 2020, 6, 164–178. Link.
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  23. Zerdoum, A. B.; Fowler, E. W.; Jia, X.* "Induction of Fibrogenic Phenotype in Human Mesenchymal Stem Cells by Connective Tissue Growth Factor in a Hydrogel Model of Soft Connective Tissue" ACS Biomat. Sci. & Eng., 2019, 5, 4531–4541. Link.
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  24. Liu, Y.; Zhang, W.; Zhang, F.; Leng, J.; Pei, S.; Wang, L.; Jia, X.; Cotton, C.; Sun, B.; Chou, T.-W..* "Microstructural Design for Enhanced Shape Memory Behavior of 4D Printed Composites Based on Carbon Nanotube/Polylactic Acid Filament" Composite Science and Technology, 2019, 181, 107692. Link.
  25. Geiger, S.; Du, Q.; Huang, B.; Shalaginov, M. Y.; Michon, J.; Lin, H.; Gu, T.; Yadav, A.; Richardson, K. A.; Jia, X.; Hu, J.* "Understanding Aging in Chalcogenide Glass Thin Films Using Precision Resonant Cavity Refractometry" Optical Materials Express, 2019, 9, 2252–2263. Link.
  26. Dicker, K. T.; Moore, A. C.; Garabedian, N. T.; Zhang, H.; Scinto, S. L.; Akins, R. E.; Burris, D. L.; Fox, J. M.*; Jia, X.* "Spatial Patterning of Molecular Cues and Vascular Cells in Fully Integrated Hydrogel Channels via Interfacial Bioorthogonal Crosslinking" ACS Appl. Mater. Interfaces, 2019, 11, 16402–16411. Link.
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  27. King, R. E.; Lau, H. K.; Zhang, H.; Sidhu, I.; Christensen, M. B.; Fowler, E. W.; Li, L.; Jia, X.; Kiick, K. L.; Thibeault, S. L.* "Biocompatibility and Viscoelastic Properties of Injectable Resilin–Like Polypeptide and Hyaluronan Hybrid Hydrogels in Rabbit Vocal Folds" Regen Eng Transl Med, 2019, 5, 373–386. Link.
  28. Zerdoum, A. B.; Stuffer, A. J.; Heris, H. K.; Liu, S.; Mongeau, L.; Duncan, R. L.; Jia, X.* "Culture of Mesenchymal Stem Cells in a Hydrogel Model of Vocal Fold Lamina Propria" Regen Eng Transl Med, 2019, 5, 387–401. Link.
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  29. Hao, Y.; Song, J.; Ravikrishnan, A.; Dicker, K. T.; Fowler, E. W.; Zerdoum, A. B.; Li, Y.; Zhang, H.; Rajasekaran, A. K.; Fox, J. M.*; Jia, X.* "Rapid Bioorthogonal Chemistry Enables in Situ Modulation of the Stem Cell Behavior in 3D without External Triggers" ACS Appl. Mater. Interfaces, 2018, 10, 26016–26027. Link.
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  30. Liu, Y.; Zhang, W.; Zhang, F.; Lan, X.; Leng, J.; Liu, S.; Jia, X.; Cotton, C.; Sun, B.; Gu, B.; Chou, T.–W.* "Shape memory behavior and recovery force of 4D printed laminated Miura–origami structures subjected to compressive loading" Composites Part B, Engineering, 2018, 153, 233–242. Link.
  31. Liu, S.; Moore, A. C.; Zerdoum, A. B.; Zhang, H.; Scinto, S. L.; Zhang, H.; Gong, L.; Burris, D. L.; Rajasekaran, A. K.; Fox, J. M;* Jia, X.* "Cellular Interactions with Hydrogel Microfibers Synthesized via Interfacial Tetrazine Ligation" Biomaterials, 2018, 180, 24–35. Link.
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  32. Dicker, K. T.; Song, J.; Moore, A. C.; Zhang, H.; Li, Y.; Burris, D. L.; Jia, X.* and Fox, J. M.* "Core–Shell Patterning of Synthetic Hydrogels Via Interfacial Bioorthogonal Chemistry for Spatial Control of Stem Cell Behavior" Chemical. Science. 2018, 9, 5394–5404. Link.
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  33. Paik, B. A.; Mane, S. R.; Jia, X.; Kiick, K. L.* "Responsive Hybrid (Poly)peptide–Polymer Conjugates" J Mater Chem. B., 2017, 5, 8274–8288.
  34. Hao, Y.; Fowler, E. W.; Jia, X.* "Chemical Synthesis of Biomimetic Hydrogels for Tissue Engineering", Polym. Int., 2017, DOI: 10.1002/pi.5407
  35. Ozdemir, T.; Srinivasan, P. P.; Zakheim, D. R.; Harrington, D. A.; Witt, R. L.; Farach–Carson, M. C.; Jia, X.*; Pradhan–Bhatt, S.* "Bottom–up Assembly of Salivary Gland Microtissues for Assessing Myoepithelial Cell Function", Biomaterials, 2017, 142, 124–135. Link.
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  36. Akkiraju, H.; Srinivasan, P. P.; Xu, X.; Jia, X.; Safran, C. B. K.; Nohe, A.* "CK2.1, a Bone Morphogenetic Protein Receptor Type Ia Mimetic Peptide, Repairs Cartilage in Mice with Destabilized Medial Meniscus", Stem Cell Res Ther., 2017, doi: 10.1186/s13287-017-0537-y.
  37. Srinivasan, P. P.; Patel, V.; Liu, S.; Harrington, D. A.; Hoffman, M. P.; Witt, R. L.; Jia, X.; Farach–Carson, M. C.; Pradhan–Bhatt, S.* "Primary Salivary Human Stem/Progenitor Cells Undergo Microenvironment–Driven Acinar–Like Differentiation in Hyaluronate Hydrogel Culture", Stem Cells Translational Medicine, 2017, 6, 110–120. Link.
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  38. Ozdemir, T.; Fowler, E. W.; Liu, S.; Harrington, D. A.; Witt, R. L.; Farach–Carson, M. C.; Pradhan–Bhatt, S.;* Jia, X.* "Tuning Hydrogel Properties to Promote the Assembly of Salivary Gland Spheroids in 3D", ACS Biomat. Sci. Eng., 2016, 2, 2217–2230. Link.
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  39. Hao, Y.; Zerdoum, A. B.; Stuffer, A. J.; Rajasekaran, A. K; Jia, X.* "Biomimetic Hydrogels Incorporating Polymeric Cell–Adhesive Peptide to Promote the 3D Assembly of Tumoroids", Biomacromolecules, 2016, 17, 3750–3760. Link.
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  40. Calero–Rubio, C.; Paik, B.; Jia, X.; Kiick, K. L.; Roberts, C. J.* "Predicting Unfolding Thermodynamics and Stable Intermediates for Alanine–Rich Helical Peptides with the Aid of Coarse–Grained Molecular Simulation", Biophys. Chem., 2016, 217, 8–19. Link.
  41. Li, L.; Stiadle, J. M; Lau, H. K.; Zerdoum, A. B.; Jia, X.; Thibeault, S. L; Kiick, K. L.* "Tissue Engineering–based Therapeutic Strategies for Vocal Fold Repair and Regeneration", Biomaterials, 2016, 108, 91–110. Link.
  42. Ravikrishnan, A.; Ozdemir, T.; Bah, M.; Baskerville, K. A.; Shah, S. I.; Ayyappan, R. K.; Jia, X.* "Regulation of Epithelial–to–Mesenchymal Transition Using Biomimetic Fibrous Scaffolds", ACS Appl. Mater. Interfaces, 2016, 8, 17915–17926. Link.
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  43. Zhang, H.; Trout, W. S.; Liu, S.; Andrade, G. A.; Hudson, D. A.; Scinto, S. L.; Dicker, K. T.; Li, Y.; Lazouski, N.; Rosenthal, J.; Thorpe, C.; Jia, X.; Fox, J. M.* "Rapid Bioorthogonal Chemistry Turn–on through Enzymatic or Long Wavelength Photocatalytic Activation of Tetrazine Ligation", J. Am. Chem. Soc., 2016, 38, 5978–5983. Link.
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  44. Ozdemir, T.; Fowler, E. W.; Hao, Y.; Ravikrishnan, A.; Harrington, D. A.; Witt, R. L.; Farach–Carson, M. C.; Pradhan–Bhatt, S.;* Jia, X.* "Biomaterials–Based Strategies for Salivary Gland Tissue Regeneration", Biomater. Sci., 2016, 4, 592–604. Link.
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  45. Li, L.; Mahara, A.; Tong, Z.; Levenson, E. A.; McGann, C. L.; Jia, X.; Yamaoka, T.; Kiick, K. L.* "Recombinant Resilin–based Bioelastomers for Regenerative Medicine Applications", Adv. Healthcare Mater., 2016, 5, 266–275. Link.
  46. Alalwiat, A.; Grieshaber, S. E.; Paik, B. A.; Kiick, K. L.; Jia, X.; Wesdemiotis, C.* "Top–down Mass Spectrometry of Hybrid Materials with Hydrophobic Peptide and Hydrophilic or Hydrophobic Polymer Blocks", Analyst, 2015, 140, 7550–7564. Link.
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  47. Li, L.; Zhang, P.; Wang, W.; Lin, H.; Zerdoum, A. B.; Geiger, S. J.; Liu, Y.; Xiao, N.; Zou, Y.; Ogbuu, O.; Du, Q.; Jia, X.; Li, J.; Hu, J.* "Foldable and Cytocompatible Sol–gel TiO2 Photonics", Sci. Rep., 2015, 13832, DOI: 10.1038/srep13832. Link.
  48. Krishnan, V.; Xu, X.; Kelly, D.; Snook, A.; Waldman, S. A.; Mason, R. W.; Jia, X.; Rajasekaran, A. K.* "CD19–Targeted Nanodelivery of Doxorubicin Enhances Therapeutic Efficacy in B–cell Acute Lymphoblastic Leukemia", Mol. Pharm., 2015, 12, 2101–2111. Link.
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  49. Liu, S.; Zhang, H.; Remy, R. A.; Deng, F.; Mackay, M. E.; Fox, J. M.*; Jia, X.* "Meter–Long Multiblock Copolymer Microfibers via Interfacial Bioorthogonal Polymerization", Adv. Mater., 2015, 27, 2783–2790. Link
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  50. Paik, B. A.; Blanco, M. A.; Jia, X.; Roberts, C. J.*; Kiick, K. L.* "Aggregation of Poly(acrylic acid)–Containing Elastin–Mimetic Copolymers", Soft Matter, 2015, 11, 1839–1850. Link
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  51. Liu, S.; Dicker, K. T.; Jia, X.* "Modular and Orthogonal Synthesis of Hybrid Polymers and Networks", Chem. Commun., 2015, 51, 5218–5237. Link
    Feature Article, Emerging Investigators issue 2015
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  52. Gilkey, M. J.; Krishnan, V.; Scheetz, L.; Jia, X.; Rajasekaran, A. K.; Dhurjati, P. S.* "Physiologically Based Pharmacokinetic Modeling of Fluorescently Labeled Block Copolymer Nanoparticles for Controlled Drug Delivery in Leukemia Therapy", CPT Pharmacometrics Syst Pharmacol, 2015, 4, 167–174. Link
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  53. Zerdoum, A. B.; Tong, Z.; Bachman, B.; Jia, X.* "Construction and Characterization of a Novel Vocal Fold Bioreactor", J. Vis. Exp., 2014, 90, e51594, doi:10.3791/51594. Link
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  54. Xu, X.; Farach–Carson, M. C.; Jia, X.* "Three–Dimensional in vitro Tumor Models for Cancer Research and Drug Evaluation", Biotechnol Adv, 2014, 32, 1256–1268. Link
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  55. Zhang, H.; Dicker, K. T.; Xu, X.; Jia, X.*; Fox, J. M.* "Interfacial Bioorthogonal Cross–linking", ACS Macro Lett, 2014, 3, 727–731. Link
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  56. Tong, Z.; Zerdoum, A. B.; Duncan, R. L.; Jia, X.* "Dynamic Vibration Cooperates with Connective Tissue Growth Factor to Modulate Stem Cell Behaviors", Tissue Eng Part A, 2014, 20, 1922–1934. Link
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  57. Xu, X.; Sabanayagam, C. R.; Harrington, D. A.; Farach–Carson, M. C.; Jia, X.* "A Hydrogel–Based Tumor Model for the Evaluation of Nanoparticle–Based Cancer Therapeutics", Biomaterials, 2014, 35, 3319–3330. Link
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  58. Dicker, K. T.; Gurski, L. A.; Pradhan–Bhatt, S.; Witt, R. L.; Farach–Carson, M. C.; Jia, X.* "Hyaluronan: A Simple Polysaccharide with Diverse Biological Functions", Acta Biomaterialia, 2014, 10, 1558–1570. Link
  59. Pradhan–Bhatt, S.; Harrington, D. A.; Duncan, R. L.; Farach–Carson, M. C.; Jia, X.; Witt, R. L.* "A Novel In Vivo Model for Evaluating Functional Restoration of a Tissue–Engineered Salivary Gland", The Laryngoscope, 2014, 124, 456–461. Link
  60. Xiao, L.; Tong, Z.; Chen, Y.; Pochan, D. J.; Sabanayagam, C. R.; Jia, X.* "Hyaluronic Acid–Based Hydrogels Containing Covalently Integrated Drug Depots: Implication for Controlling Inflammation in Mechanically Stressed Tissues", Biomacromolecules, 2013, 14, 3808–3819. Link
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  61. Yang, X.; Xiao, L.; Jia, X.* "Designing Mechano–Responsive Materials with Elastomeric Properties for Biomedical Applications", SurFACTS in Biomaterials, 2013, 18, 7–8. Link
  62. Yang, X.; Cui, C.; Tong, Z.; Sabanayagam, C. R.; Jia, X.* "Poly(ε–Caprolactone)–Based Copolymers Bearing Pendant Cyclic Ketals and Reactive Acrylates for the Fabrication of Photocrosslinked Elastomers", Acta Biomaterialia, 2013, 9, 8232–8244. Link
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  63. Tong, Z.; Duncan, R. L.; Jia, X.* "Modulating the Behaviors of Mesenchymal Stem Cells via the Combination of High–Frequency Vibratory Stimulations and Fibrous Scaffolds", Tissue Eng Part A, 2013, 19, 1862–1878. Link
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  64. Farran, A. J. E.; Teller, S. S.; Jia, F.; Clifton, R. J.; Duncan, R. L.; Jia, X.* "Design and Characterization of a Dynamic Vibrational Culture System", J. Tissue Eng Regen. M., 2013, 7, 213–225. Link
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  65. Pradhan–Bhatt, S.; Harrington, D. A.; Duncan, R. L.; Jia, X.; Witt, R. L.; Farach–Carson, M. C*. "Implantable Three–Dimensional Salivary Spheroid Assemblies Demonstrate Fluid and Protein Secretory Responses to Neurotransmitters", Tissue Eng Part A, 2013, 19, 1610–1620. Link
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  66. Krishnan, V.; Xu, X.; Barwe, S. P.; Yang, X.; Czymmek, K.; Waldman, S. A.; Mason, R. W.; Jia, X.; Rajasekaran, A. K.* "Dexamethasone–Loaded Block Copolymer Nanoparticles Induce Leukemia Cell Death and Enhance Therapeutic Efficacy: A Novel Application in Pediatric Nanomedicine", Mol. Pharm., 2013, 10, 2199–2210. Link
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  67. Li, L.; Tong, Z.; Jia, X.; Kiick, K. L.* "Resilin–Like Polypeptide Hydrogels Engineered for Versatile Biological Function", Soft Matter, 2013, 9, 665–673. Link
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  68. Grieshaber, S. E.; Paik, B. A.; Bai, S.; Kiick, K. L.; Jia, X.* "Nanoparticle Formation from Hybrid, Multiblock Copolymers of Poly(acrylic acid) and a VPGVG Peptide", Soft Matter, 2012, 9, 1589–1599. Link
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  69. Gurski, L. A.; Xu, X.; Labrada, L. N.; Nguyen, N. T.; Xiao, L.; van Golen, K. L.; Jia, X.; Farach–Carson, M. C.* "Hyaluronan (HA) Interacting Proteins RHAMM and Hyaluronidase Impact Prostate Cancer Cell Behavior and Invadopodia Formation in 3D HA–Based Hydrogels", PLoS One, 2012, 7, e50075. Link
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  70. Xu, X.; Gurski, L. A.; Zhang, C.; Harrington, D. A.; Farach–Carson, M. C.; Jia, X.* "Recreating the Tumor Microenvironment in a Bilayer, Hyaluronic Acid Hydrogel Construct for the Growth of Prostate Cancer Spheroids", Biomaterials, 2012, 33, 9049–9060. Link
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  71. Xiao, L.; Zhu, J.; Londono, D. J.; Pochan, D. J.; Jia, X.* "Mechano–Responsive Hydrogels Crosslinked by Block Copolymer Micelles", Soft Matter, 2012, 8, 10233–10237. Link
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  72. Teller, S. S.; Farran, A. J. E.; Xiao, L.; Jiao, T.; Duncan, R. L.; Clifton, R. J.; Jia, X.* "High–Frequency Viscoelastic Shear Properties of Vocal Fold Tissues: Implications for Vocal Fold Tissue Engineering", Tissue Eng Part A, 2012, 18, 2008–2019. Link
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  73. Tong, Z.; Jia, X.* "Biomaterial–Based Strategies for the Engineering of Mechanically Active Soft Tissues", MRS Commun, 2012, 2, 31–39. Link
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  74. Grieshaber, S. E.; Farran, A. J. E.; Bai, S.; Kiick, K. L.*; Jia, X.* "Tuning the Properties of Elastin Mimetic Hybrid Copolymers via a Modular Polymerization Method", Biomacromolecules, 2012, 13, 1774–1786. Link
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  75. Xu, X.; Jha, A. K.; Harrington, D. A.; Farach–Carson, M. C.; Jia, X.* "Hyaluronic Acid–Based Hydrogels: from a Natural Polysaccharide to Complex Networks", Soft Matter, 2012, 8, 3280–3294. Link
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  76. Srinivasan, P. P.; McCoy, S. Y.; Jha, A. K.; Yang, W.; Jia, X.*; Farach–Carson, M. C.; Kirn–Safran, C. B.* "Injectable Perlecan Domain 1–Hyaluronan Microgels Potentiate the Cartilage Repair Effect of BMP2 in a Murine Model of Early Osteoarthritis", Biomed. Mater., 2012, 7, 024109 (11pp). Link
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  77. Tong, Z.; Sant, S.; Khademhosseini, A.*; Jia, X.* "Controlling the Fibroblastic Differentiation of Mesenchymal Stem Cells via the Combination of Fibrous Scaffolds and Connective Tissue Growth Factor", Tissue Eng Part A, 2011, 17, 2773–2785. Link
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  78. Krishna, O. D.; Jha, A. K.; Jia, X.*; Kiick, K. L.* "Integrin–Mediated Adhesion and Proliferation of Human MSCs Elicited by a Hydroxyproline–Lacking, Collagen–like Peptide", Biomaterials, 2011, 32, 6412–6424. Link
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  79. Xu, X.; Jha, A. K.; Duncan, R. L.; Jia, X.* "Heparin–Decorated, Hyaluronic Acid–Based Hydrogel Particles for the Controlled Release of Bone Morphogenetic Protein 2", Acta Biomaterialia, 2011, 7, 3050–3059. Link
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  80. Li, L.; Teller, S.; Clifton, R. J.; Jia, X.; Kiick, K. L.* "Tunable Mechanical Stability and Deformation Response of a Resilin–based Elastomer", Biomacromolecules, 2011, 12, 2302–2310. Link
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  81. Greene, A. C.; Zhu, J.; Pochan, D. J.; Jia, X.*; Kiick, K. L.* "Poly(Acrylic Acid–b–Styrene) Amphiphilic Multiblock Copolymers as Building Blocks for the Assembly of Discrete Nanoparticles", Macromolecules, 2011, 44, 1942–1951. Link
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  82. Wang, X.; Gurski, L. A.; Zhong, S.; Xu, X.; Pochan, D. J.; Farach–Carson, M. C.; Jia, X.* "Amphiphilic Block Co–polyesters Bearing Pendant Cyclic Ketal Groups as Nanocarriers for Controlled Release of Camptothecin", J. Biomat. Sci.–Polym. E., 2011, 22, 1275–1298. Link
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  83. Jha, A. K.; Xu, X.; Duncan, R. L.; Jia, X.* "Controlling the Adhesion and Differentiation of Mesenchymal Stem Cells Using Hyaluronic Acid–based, Doubly Crosslinked Networks", Biomaterials, 2011, 32, 2466–2478. Link
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  84. Grieshaber, S. E.; Nie, T.; Yan, C.; Zhong, S.; Teller, S. S.; Clifton, R. J.; Pochan, D. J.; Kiick, K. L.; Jia, X.* "Assembly Properties of an Alanine–Rich, Lysine–Containing Peptide and the Formation of Peptide/Polymer Hybrid Hydrogels", Macromol. Chem. Phys., 2011, 212, 229–239. Link
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  85. Xiao, L.; Liu, C.; Zhu, J.; Pochan, D. J.; Jia, X.* "Hybrid, Elastomeric Hydrogels Crosslinked by Multifunctional Block Copolymer Micelles", Soft Matter, 2010, 6, 5293–5297. Link
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  86. Jha, A. K.; Malik, M. S.; Farach–Carson, M. C.; Duncan, R. L.; Jia, X.* "Hierarchically Structured, Hyaluronic Acid–Based Hydrogel Matrices via the Covalent Integration of Microgels into Macroscopic Networks", Soft Matter, 2010, 6, 5045–5055. Link
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  87. Luo, Y.*; Kobler, J. B.; Heaton, J. T.; Jia, X.; Zeitels, S. M.; Langer, R. "Injectable Hyaluronic Acid–Dextran Hydrogels and Effects of Implantation in Ferret Vocal Fold", J. Biomed. Mater. Res. B, 2010, 93B, 386–393. Link
  88. Pradhan, S.; Liu, C.; Zhang, C.; Jia, X.; Farach–Carson, M. C.; Witt, R. L.* "Lumen Formation in Three–Dimensional Cultures of Salivary Acinar Cells", Otolaryngol. Head Neck Surg., 2010, 142, 191–195. Link
  89. Gurski, L. A.; Petrelli, N. J.; Jia, X.; Farach–Carson, M. C.* "3D Matrices for Anti–Cancer Drug Testing and Development", Oncology Issues, 2010, 25, 20–25.
  90. Farran, A. J. E.; Teller, S. S.; Jha, A. K.; Jiao, T.; Hule, R. A.; Clifton, R. J.; Pochan, D. J.; Duncan, R. L.; Jia, X.* "Effects of Matrix Composition, Microstructure, and Viscoelasticity on the Behaviors of Vocal Fold Fibroblasts Cultured in Three–Dimensional Hydrogel Networks", Tissue Eng Part A, 2010, 16, 1247–1261. Link
  91. Jha, A. K.; Yang, W.; Kirn–Safran, C. B.; Farach–Carson, M. C.; Jia, X.* "Perlecan Domain I–Conjugated, Hyaluronic Acid–Based Hydrogel Particles for Enhanced Chondrogenic Differentiation via BMP–2 Release", Biomaterials, 2009, 30, 6964–6974. Link
  92. Pradhan, S.; Zhang, C.; Jia, X.; Carson, D. D.; Witt, R.; Farach–Carson, M. C.* "Perlecan Domain IV Peptide Stimulates Salivary Gland Cell Assembly in vitro", Tissue Eng Part A, 2009, 15, 3309–3320. Link
  93. Gurski, L. A.; Jha, A. K.; Zhang, C.; Jia, X.; Farach–Carson, M. C.* "Hyaluronic acid–based hydrogels as 3D matrices for in vitro evaluation of chemotherapeutic drugs using poorly adherent prostate cancer cells", Biomaterials, 2009, 30, 6076–6085. Link
  94. Grieshaber, S. E.; Farran, A. J. E.; Lin–Gibson, S.; Kiick, K. L.*; Jia, X.* "Synthesis and Characterization of Elastin–Mimetic Hybrid Polymers with Multiblock, Alternating Molecular Architecture and Elastomeric Properties", Macromolecules, 2009, 42, 2532–2541. Link
  95. Jia, X.*; Kiick, K. L.* "Hybrid Multicomponent Hydrogels for Tissue Engineering", Macromol. Biosci., 2009, 9, 140–156. Link
  96. Jiao, T.*; Farran, A.; Jia, X.; Clifton, R. J. "High Frequency Measurements of Viscoelastic Properties of Hydrogels for Vocal Fold Regeneration", Exp. Mech., 2009, 49, 235–246. Link
  97. Jha, A. K.; Hule, R. A.; Jiao, T.; Teller, S. S.; Clifton, R. J.; Duncan, R. L.; Pochan, D. J.; Jia, X.* "Structural Analysis and Mechanical Characterization of Hyaluronic Acid–Based Doubly Cross–Linked Networks", Macromolecules, 2009, 42, 537–546. Link
  98. Sahiner, N.; Jha, A. K.; Nguyen, D.; Jia, X.* "Fabrication and Characterization of Cross–Linkable Hydrogel Particles Based on Hyaluronic Acid: Potential Application in Vocal Fold Regeneration", J. Biomat. Sci.–Polym. E., 2008, 19, 223–243. Link
  99. Ni, C.*; Li, X.; Chen, Z.; Li, H.–Y. H.; Jia, X.; Shah, I.; Xiao, J. Q. "Oriented Polycrystalline Mesoporous CeO2 with Enhanced Pore Integrity", Micropor. Mesopor. Mat., 2008, 115, 247–252. Link
  100. Goldberg, M.; Langer, R.; Jia, X.* "Nanostructured Materials for Applications in Drug Delivery and Tissue Engineering", J. Biomat. Sci.–Polym. E., 2007, 18, 241–268. Link
  101. Jia, X.*; Yeo, Y.; Clifton, R. J.; Jiao, T.; Kohane, D. S.; Kobler, J. B.; Zeitels, S. M.; Langer, R. "Hyaluronic Acid–Based Microgels and Microgel Networks for Vocal Fold Regeneration", Biomacromolecules, 2006, 7, 3336–3344. Link
  102. Jia, X.*; Herrera–Alonso, M.; McCarthy, T. J. "Nylon Surface Modification. Part 1. Targeting the Amide Groups for Selective Introduction of Reactive Functionalities", Polymer, 2006, 47, 4916–4924. Link
  103. Herrera–Alonso, M.; McCarthy, T. J.; Jia, X.* "Nylon Surface Modification:  2. Nylon–Supported Composite Films", Langmuir, 2006, 22, 1646–1651. Link
  104. Clifton, R. J.*; Jiao, T.; Bull, C.; Jia, X. "Vocal Fold Bioengineering", Science & Medicine, 2005, 10, 149–152. Link
  105. Burdick, J. A.; Chung, C.; Jia, X.; Randolph, M. A.; Langer, R.* "Controlled Degradation and Mechanical Behavior of Photopolymerized Hyaluronic Acid Networks", Biomacromolecules, 2005, 6, 386–391. Link
  106. Jia, X.; Burdick, J. A.; Kobler, J.; Clifton, R. J.; Rosowski, J. J.; Zeitels, S. M.; Langer, R.* "Synthesis and Characterization of in Situ Cross–Linkable Hyaluronic Acid–Based Hydrogels with Potential Application for Vocal Fold Regeneration", Macromolecules, 2004, 37, 3239–3248. Link
  107. Jia, X.; Colombo, G.; Padera, R.; Langer, R.; Kohane, D. S.* "Prolongation of Sciatic Nerve Blockade by in Situ Cross–Linked Hyaluronic Acid", Biomaterials, 2004, 25, 4797–4804. Link
  108. Kim, D. H.; Jia, X.; Lin, Z.; Guarini, K. W.; Russell, T. P.* "Growth of Silicon Oxide in Thin Film Block Copolymer Scaffolds", Adv. Mater., 2004, 16, 702–706.
  109. Jia, X.; McCarthy, T. J.* "Controlled Growth of Silicon Dioxide from “Nanoholes” in Silicon–Supported Tris(trimethylsiloxy)silyl Monolayers: Rational Control of Surface Roughness at the Nanometer Length Scale", Langmuir, 2003, 19, 2449–2457.
  110. Ming, W.*; Tian, M.; van de Grampel, R. D.; Melis, F.; Jia, X.; Loos, J.; van der Linde, R. "Low Surface Energy Polymeric Films from Solventless Liquid Oligoesters and Partially Fluorinatedd Isocyanates", Macromolecules, 2002, 35, 6920–6929.
  111. Jia, X.; McCarthy, T. J.* "Buried Interface Modification Using Supercritical Carbon Dioxide", Langmuir, 2002, 18, 683–687.
  112. Kim, H. C.; Jia, X.; Stafford, C. M.; Kim, D. H.; McCarthy, T. J.; Tuominen, M.; Hawker, C. J.; Russell, T. P.* "A Route to Nanoscopic SiO2 Posts via Block Copolymer Templates", Adv. Mater., 2001, 13, 795–797.
  113. Jia, X.; Pang, Y.; Huang, J.* "Copolymerization of Ethyl α–(Hydroxymethyl)acrylate with Maleimide and Characterization of the Resulting Copolymer", J. Polym. Sci. A1, 1998, 36, 1291–1299.
  114. Jiang, J.; Jia, X.; Pang, Y.; Huang, J.* "Alternating Copolymerization of Maleimide and Ethyl Atropate without Initiator", J. Macromol. Sci. Pure, 1998, A35, 781–792.

Books and Book Chapters

  1. Grieshaber, S. E.; Jha, A. K.; Farran, A. J. E.; Jia, X., "Hydrogels in Tissue Engineering" in "Biomaterials for Tissue Engineering: A review of the past and future trends" Burdick, J. A.; Mauck, R. L. Eds. Springer, 2011, 9–46 (ISBN: 978–3–7091–0384–5).
  2. Farran, A. J. E.; Tong, Z.; Witt, R. L.; Jia, X., "Tissue Engineering Strategies for Vocal Fold Repair and Regeneration" in "Engineering Biomaterials for Regenerative Medicine: Novel Technologies for Clinical Applicaations" Bhatia, S. K. Ed., Springer, 2012, 253–284 (ISBN: 978–1–4614–1080–5).

Patents

  1. Kirn–Safran, C. B.; Farach–Carson, M. C.; Jia, X.; Srinivasan, P. P.; Jha, A. J., "Injectable Delivery System for Heparin–Binding Growth Factors", Provisional Patent Application, US 61/453,340, April 14, 2011.
  2. Jia, X.; Jia, M.; Jha, A. K.; Farran, A. J. E.; Tong, Z., "Dynamic Vibrational Method and Device for Vocal Fold Tissue Growth", Nonprovisional Patent Application, US 12/781,305, May 15, 2010.
Xinqiao JiaDepartment of Materials Science and Engineering
201 Pierre S. du Pont Hall
Newark, DE 19716 • USA
Phone: 302–831–6553 • Fax: 302–831–4545
Email: xjia@udel.edu • © 2021