Muhammed Shafeekh Muyyarikkandy

Research Interest

Muyyarikkandy lab’s research is focused on the One Health approach, emphasizing the intricate connection between human, animal, and environmental health. With a specialized focus on host-pathogen interaction and combating antimicrobial resistance from foodborne infections, our research probes into disease transmission and development mechanics, particularly in the context of zoonotic diseases and antimicrobial resistance. This work is crucial for developing innovative treatments and preventative strategies and plays a pivotal role in predicting and controlling disease outbreaks. By understanding the dynamics of host-pathogen interactions, our research contributes to the broader One Health initiative, offering insights instrumental in shaping effective public health policies and practices.

Our research approach hypothesizes that the altered intracellular redox status in host tissues elicits oxidative damage to intracellular pathogens. To test this, we utilize dietary interventions in animal models such as chickens and mice to alter intracellular redox status, aiming to reduce the incidence of subclinical intracellular pathogens. This strategy has the potential to mitigate antibiotic resistance in foodborne bacterial pathogens. In addition, recognizing that many disease manifestations result from altered microbiomes rather than the pathogens themselves, we also focus on replenishing a healthy gut environment using culturome to prevent major foodborne pathogens.

Resources and links

• Google scholar
• LinkedIn

Education

• Ph.D., Animal Science - Food Microbiology and Safety (University of Connecticut, Storrs, CT)
• M.S., Animal Science (University of Connecticut, Storrs, CT)
• B.V.Sc. & A.H. (equivalent to D.V.M.) (Kerala Veterinary and Animal Sciences University, Wayanad, India)

Professional activity

• American Society of Microbiology
• American Society of Nutrition
• Poultry Science Association
• Conference of Research Workers in Animal Diseases