Joohyun (Jason) Lim

Education

• B.S., Pennsylvania State University, University Park, PA
• M.S., University of California, Irvine, CA
• Ph.D., Washington University in St. Louis, MO
• Postdoc, Baylor College of Medicine, Houston, TX​
   

Teaching

• BISC415/615 - Developmental Biology (Spring)​
  

Research Interests

Our research is focused on understanding how individual components in joint tissues, including the tendon, bone, and cartilage, are formed and maintained throughout life. Cells residing in these adjacent yet distinct tissues are regulated by unique mechanisms (Lim et al. 2016, Lim et al. 2017). Furthermore, abnormalities in these musculoskeletal resident cell populations can contribute to disease such as osteoarthritis (OA) or temporomandibular joint OA (TMJ-OA) which affects over 15 million individuals in the United States.

Our overarching goal is (1) to investigate mechanisms of cell differentiation and function that are essential for the development and maintenance of unique cell types that reside in the TMJ, and (2) to determine how alterations in these mechanisms contribute to TMJ-OA and temporomandibular disorders (TMDs). We will address these questions by using multi-disciplinary approaches, including state-of-the-art imaging techniques, single cell and spatial transcriptomics, mouse genetic tools, and 3D in vitro culture models.