Andre Luiz Pasqua Tavares
Andre Luiz Pasqua Tavares
Assistant Professor
Office: 322 Wolf Hall
Lab: 262 Wolf Hall
Resources and Links
Education
- D.D.S. – Federal University of Alfenas
- MS. – Federal University of Minas Gerais
- Ph.D. – Federal University of Minas Gerais
- Postdoctoral – University of Arizona and University of Colorado Anschutz Medical Campus
Research Interests
Our goal is to determine the role of the transcription factor SIX1 and SIX1-associated genes in development of the cranial bones, jaws and ear using transgenic mice and Xenopus (frog).
Our overarching goal is to help patients and their families understand the genetic causes of SIX1-related birth defects (e.g., branchio-oto-renal syndrome, craniosynostosis), and to develop preventive and corrective strategies.
Current Projects
- Six1 role during skull bone and suture development and disease: Analyzing the role of Six1 and Six1-associated genes in development of the mouse cranial bones and sutures; Determining the link between Six1 and the pathogenesis of premature suture closure (craniosynostosis)
- Six1 co-factors function during development of the jaws and ear: Uncovering the function of Six1-associated genes (co-factors) during development of the craniofacial cartilages and inner ear in Xenopus (frog); Dissecting the role of Six1 co-factors during development of the jaws and middle ear in mouse.
- Six1 and co-factors role during tooth development: Determining the function of Six1 and Six1 co-factors during incisor development in mouse.
